p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
Gastrointestinal Disorders | Free Full-Text | Prognostic Impact of TP53 Mutations and Tumor Mutational Load in Colorectal Cancer
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram
A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer - Frontiers
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers - ScienceDirect
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm | ACS Chemical Biology
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma
Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages - Behring - 2019 - Molecular Genetics & Genomic Medicine - Wiley Online Library
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions | eLife
Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties | Science Translational Medicine
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies
Probability Distributions of p53 Mutations and Their Corresponding Shannon Entropies in Different Cancer Cell Types | SpringerLink
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery
TP53 mutations predict poor response to immunotherapy in patients with metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online Library
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
